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Vacancies Vacancies: Postdoctoral Scholars in Drug Discovery
Posted byEuclockmanagement on Thursday, July 19 @ 13:38:06 CEST
Contributed by Euclockmanagement

Neuropharmacology of Melatonin Receptors and Circadian Rhythms

A postdoctoral research position supported by NIH funding is available immediately for a Ph.D.
or MD/Ph.D. to work on the role of MT1 and MT2 melatonin receptors in the modulation of
circadian rhythms alterations and dopaminergic sensitization induced by drugs of abuse. Projects
include the use of mouse models with genetic deletion of the MT1 and/or MT2 melatonin
receptors and/or clock genes, and the identification of novel drugs for the treatment of insomnia,
depression, and circadian sleep disorders.

Candidates must have a strong research background and practical experience with mammalian
clock gene expression, circadian rhythms of behavior, and brain surgical procedures. Knowledge
of electrophysiological techniques and the molecular neuropharmacology of G-protein coupled
receptors is also desired. Candidates should be willing to use integrated circadian in vitro and in
vivo approaches to assess the role of drugs of abuse on clock gene expression and circadian
behaviors. This position represents a unique opportunity for career development, for learning the
neuropharmacology of circadian rhythms and drug discovery, and for interactions with
investigators within the multidisciplinary scientific community at Northwestern University.

Applications should include a cover letter summarizing career experiences and specific
qualifications in the field of circadian rhythm neurobiology, a CV, and full contact information
for at least 3 references.
Submit applications directly Dr. Margarita L. Dubocovich [[email protected]; (312) 503-8005].
Deadline for receipt of completed applications is August 15, 2007. AA/EOE. We encourage applications from women and members of
underrepresented groups.

Contact Dr. Margarita L. Dubocovich:
E-mail: [email protected]
Phone: (312) 503-8005


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